Elon Musk's SpaceX
 was involved in making
 3D
 printing history at 1:52 a.m. EST today, when its Dragon spacecraft 
launched on a cargo mission to the International Space Station for NASA 
with a 3D printer in tow. Not only is this the first 3D printer in 
space, it will become the 
first manufacturing device used 
off-Earth. This isn't any off-the-shelf model 3D printer; this printer 
had to be specially built to function in a zero-gravity -- or "zero G" 
-- environment.
First let's look at the company that made today's historic event 
possible and its plans to develop a commercially available 3D printing 
production facility on the ISS, and then explore the potential long-term
 ramifications for 3D printing industry investors.
The ISS' robotic arm grappling Dragon on a previous cargo mission for NASA. Source: SpaceX.
The sky is no longer the limit for 3D printingMade
 In Space is the privately held company that designed and built the 3D 
printer that's making history. It was founded in 2010 out of a NASA Ames
 Research Center program at Singularity University and is cozily based 
at Ames.
The company was founded with the goal of bringing 3D printing -- 
technically called "additive manufacturing," since the technology 
involves building a component layer by layer -- to the space industry. 
The founding group is comprised of space veterans (including an 
astronaut), 3D printing experts, and several entrepreneurs. Among the 3D
 printing specialists is a Bespoke Innovations co-founder who's a 
director at 
Autodesk  (
NASDAQ: ADSK  ) . Bespoke was acquired by 
3D Systems  (
NYSE: DDD  )
  in 2012; Autodesk makes design software for 3D printing and other 
applications, and, in fact, Made In Space used Autodesk's software to 
design its 3D printer.
Made In Space's mission started in early 2013 when it was awarded a 
Phase 3 Small Business Innovation Research contract with NASA's Marshall
 Space Flight Center to provide the 3D printer for the ISS mission. The 
project is dubbed the "3D Printing in Zero-G Experiment."
Constructing a 3D printer for a trip to space was no simple task. It 
involved more than 20,000 hours of testing of various off-the-shelf and 
custom-built 3D printers, and dozens of components. Ultimately, Made In 
Space had to design and build an extrusion-based printer from the ground
 up to ensure that it would function reliably in microgravity and meet 
NASA's stringent safety and operational requirements. The printer was 
"ruggedized" to survive launch and the hardware was designed so parts 
aren't floating around or moving when they are not supposed to.
Three 3D printers the company built were simulation-tested to see 
what the effects of microgravity would be. This was accomplished via 
parabolic airplane flights, which produce short periods of 
weightlessness. Of course, the 3D printer that would ultimately be 
launched into space needed to be NASA-certified. This process involved 
subjecting it to a series of tests at NASA's Marshall Space Flight 
Center, including electromagnetic interference, vibration, materials 
compliance, human factors, electrical, and ISS interface checks.
The 3D printer will print a series of test parts and tools, including
 the first item ever manufactured off-planet. Printing won't likely 
begin until the end of this year, as there are live rodent experiments 
on the ISS that need to take first priority. 
The Made In Space 3D printer that's en route to the ISS. Source: Made In Space.
One small step for a 3D printer, one giant leap for 3D printing in spaceMade
 In Space will use its findings from this mission to develop a second 3D
 printer that will be permanently installed on the ISS. This printer 
will be a part of the company's Additive Manufacturing Facility, or AMF.
 The equipment for this facility is expected to launch to the ISS in 
2015.
Being able to produce spare parts and tools in space will be 
tremendously valuable to NASA and astronauts. Currently, NASA has to 
launch considerably more parts than any mission will need. After all, 
it's not like astronauts can make speedy jaunts to 
Home Depot or call a contractor like we earthlings can if we're in need of a quick fix.
This fact illustrates the potential for 3D printing to make life in 
space easier and considerably less costly: "Our first 3D printer will be
 capable of building an estimated 30% of the parts that NASA has already
 needed to repair on the ISS," said Jason Dunn, CTO of Made In Space, in
 a press release.
The printer that was just launched into space can produce components 
made of ABS plastic, which is the plastic from which Legos are made. 
Grant Lowery, Made In Space's marketing and communications manager, told
 me by phone this week that the 3D printer that will be part of the AMF 
in 2015 will have increased materials capabilities and also a larger 
build box than the first-generation printer. Thus, AMF's 3D printer will
 surely increase Dunn's 30% figure quoted above. (As to the additional 
materials, Lowery wasn't at liberty to discuss this topic.)
Ultimately, NASA's goal is to include 3D printers on space missions. 
Beyond the moneysaving and convenience factors, there's the safety 
aspect. There's no way even a group of rocket scientists can foresee 
every conceivable emergency scenario. So, having a 3D printer on board 
to crank out a jerry-rigged fix on space missions could be life-saving.
3D printing in space could kick-start a new space economyOne
 of the most interesting facets of the AMF is that Made In Space plans 
to make it commercially available. So beyond astronauts, companies 
involved in constructing small satellites and independent researchers on
 the ISS could also benefit from the AMF. Additionally, beyond servicing
 existing businesses, Lowery told me that Made In Space envisions the 
AMF as an "incubator for new businesses."
There are also some mind-blowing longer-term possibilities. Lowery 
said the company foresees its printers eventually being able to use 
asteroid material as feedstock. The benefit is obvious: The entire 3D 
printing-in-space process would be self-sufficient, as it would 
eliminate the need for feedstock from Earth to be launched into space. 
Launching anything into space is a huge expense, as it currently costs 
several thousand dollars per pound to put anything from Earth into 
low-Earth orbit.
A few companies, such as Planetary Resources and Deep Space 
Industries, have recently formed with the goal of mining asteroids. 
Scientists believe that asteroids are likely made of all the ingredients
 necessary to live in space. The aim of these companies is to supply the
 raw materials to support a new space economy.
Self-sufficiency, or at least near self-sufficiency, is a must if 
humans are to eventually colonize other planets, such as Mars. Some 
people, including SpaceX founder and chairman Elon Musk, believe this 
will occur within 20 years.
The sky is no longer the limit for 3D printing... profitsThe
 market size for 3D printing could expand in an out-of-this-world way if
 3D printing expands to a literal out-of-this-world technology. It seems
 safe to say that it's not a question of "if," just "when." NASA is 
gung-ho about 3D printing, as is much of the aerospace industry, and 
it's already using this amazing technology for various other 
applications. Additionally, where there's big money to be had, 
innovative entrepreneurs usually step up to the challenge.
According to Wohlers Report 2014, the global 3D printing industry is 
expected to grow from $3.07 billion in 2013 to more than $21 billion by 
2020; that's greater than a 31% compounded annual growth rate. If and 
when -- again, I think it's a "when" -- 3D printing starts being used in
 space applications beyond testing, Wohlers' estimates could prove to be
 conservative. While we surely won't see an explosion in the use of 3D 
printing in space within the next six years, it seems within the realm 
of possibility that there could be some significant investments in the 
space applications of the technology by 2020.
The bigger 3D printing's market size, the greater the potential 
profits in the 3D printing industry. Made In Space is privately held, 
which means it doesn't offer publicly traded stock. It's certainly too 
soon for any speculation as to what the company's future holds, as we 
need to wait to see how well its 3D printer functions in space. If it 
functions well, and the company continues to make solid progress on its 
mission, it seems likely there will eventually be a public company 
tie-in. Going public or partnering with a publicly traded company is 
often the best way of raising a considerable amount of capital for 
growth purposes. Surely, both 3D printing bigwigs, 3D Systems and 
Stratasys  (
NASDAQ: SSYS  ) , would want a piece of the space action. There are numerous other captivating possibilities.